Cow gut enzyme CRhAB breaks superbug shields, revives antibiotic power
GS3Economy · S&T · Environment · Security· Biotechnology & health research· Prelims·
Why in news
Scientists at IISc Bengaluru discovered the cow gut enzyme CRhAB, which can break down biofilms of antibiotic-resistant superbugs.
Background
Researchers at the Indian Institute of Science (IISc) Bengaluru identified the CRhAB enzyme in cow gut. It specifically targets biofilms of superbugs like Acinetobacter baumannii and Klebsiella pneumoniae to restore antibiotic efficacy.
Facts for Prelims
- S&TCRhAB: An enzyme derived from cow gut that breaks down bacterial biofilms.
- S&TAcinetobacter baumannii and Klebsiella pneumoniae: Examples of 'superbugs' prone to hospital-acquired infections.
- BodyIISc Bengaluru: The primary research institution involved in this biotech discovery.
For Mains
Q. Discuss the growing threat of antimicrobial resistance (AMR) and the role of biotechnology in developing novel therapies to combat superbugs.
Dimensions to cover in your answer
- rise of multi-drug resistant organisms (MDROs)
- biotech innovations in enzyme therapy
- public health implications of hospital-acquired infections
Keywords: Antimicrobial Resistance (AMR) · Biofilms · Superbugs · Biotechnology · Enzyme Therapy
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