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VOL. I · EST. 11.2025 
SatyaDheesh
सत्याधीश
India's Ground Truth Record
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Standard diabetes test glycated haemoglobin (HbA1c) may mislead in diagnosis of type-2 diabetes in India’s population: experts

GS2Polity · Governance · IR· Health policy & public health· Mains·

Why in news

Experts and a study in Lancet Regional Health argue that the HbA1c test may mislead type-2 diabetes diagnosis in India due to high prevalence of anemia and G6PD deficiency.

Background

The study published in Lancet Regional Health: Southeast Asia suggests a multiparametric approach for diabetes diagnosis in South Asia. Experts include Dr. Anoop Misra of Fortis C-DOC Centre of Excellence for Diabetes and Shashank Joshi of Joshi Clinic, Mumbai.

Facts for Prelims

  • S&THbA1c: A standard test used for diagnosing and monitoring type-2 diabetes.
  • FactG6PD deficiency and haemoglobinopathies are identified as factors that can mislead HbA1c results in the Indian population.
  • S&TMultiparametric approach: Includes oral glucose tolerance tests, self-monitoring of blood glucose, and continuous glucose monitoring.

For Mains

Q. Discuss the challenges in standardizing non-communicable disease diagnostics in India's diverse population and suggest a multiparametric framework for accurate healthcare delivery.

Dimensions to cover in your answer

  • Diagnostic inaccuracy: High prevalence of anemia and G6PD deficiency confounding HbA1c results in South Asian phenotypes
  • Clinical oversight: Need for integrating hematologic assessments with biochemical markers to prevent misdiagnosis
  • Technological equity: Balancing the adoption of continuous glucose monitoring with rural healthcare accessibility

Keywords: Non-communicable diseases · Diagnostic accuracy · Multiparametric approach · Public health infrastructure · Epidemiological diversity

Read the full news →Source: The Hindu ↗Also: GS3 · Biotechnology & health research

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This note is generated automatically from SatyaDheesh's news feed and mapped to the UPSC CSE syllabus. Check facts against the original report or PIB before using them in an answer.