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VOL. I · EST. 11.2025 
SatyaDheesh
सत्याधीश
India's Ground Truth Record
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IIT Bombay Scientists Simplify Drug Discovery, Create Anti-Cancer Molecule

GS3Economy · S&T · Environment · Security· Biotechnology & health research· Prelims·

Why in news

IIT Bombay scientists developed a novel chemical synthesis method to convert straight-chain carbon compounds into ring-shaped molecules to accelerate anti-cancer drug discovery.

Background

The research, led by Professor Debabrata Maiti, was published in the journal Nature. The team successfully synthesized over 10 biologically relevant molecules, including the anti-cancer compound muricatacin, using this streamlined method.

Facts for Prelims

  • S&TMuricatacin: A bioactive compound with documented anti-cancer properties.
  • BodyIIT Bombay: An Institute of National Importance under the Ministry of Education.
  • FactThe new method reduces the multi-step complexity of traditional ring-shaped molecule synthesis.

For Mains

Q. How can advancements in synthetic chemistry and biotechnology accelerate India's goal of becoming a global hub for affordable pharmaceutical manufacturing?

Dimensions to cover in your answer

  • R&D bottleneck: High costs of multi-step chemical synthesis hindering the development of novel small-molecule drugs.
  • Sustainability shift: Transitioning from complex, waste-heavy chemical processes to streamlined, efficient molecular synthesis.
  • IPR landscape: Balancing open-source academic breakthroughs with private pharmaceutical patenting for commercial drug viability.

Keywords: Synthetic Chemistry · Drug Discovery · Biotechnology · Pharmaceutical Innovation · Sustainable Chemistry

Read the full news →Report a mistake in this noteSource: Indian Express ↗Also: GS3 · Industry, investment & MSMEs

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